It is possible to classify more accurately a considerable variety of ophthalmic lesions through more, though incomplete, knowledge of the humoral and cellular elements involved. By correlating recent discoveries in biochemistry, clinical medicine and pathology, the ophthalmologist is able to simplify his understanding of a variety of disease processes in the eye. From a study of a series of cellular interactions a confusion of histopathologic patterns arises. However, in these patterns common underlying changes are noted and used as a basis for classifying some ocular disease syndromes. Any position taken must be tentative because of the incompleteness of knowledge.
By histiocytosis are meant the immune reactions of an intermediate metabolic tissue having properties of phagocytosis prominent in inflammation. These properties are not exclusive with the cells of the histiocytic apparatus.1 By storage are meant the reactions following intracellular accumulations, chiefly leading to fibroblastic proliferation and