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Article
October 1933

CATARACT IN THE ALBINO MOUSE RESULTING FROM A DEFICIENCY OF VITAMIN G (B2)

Author Affiliations

LITTLE ROCK, ARK.
From the Departments of Anatomy, Physiological Chemistry and Ophthalmology, School of Medicine, University of Arkansas.

Arch Ophthalmol. 1933;10(4):508-514. doi:10.1001/archopht.1933.00830050084010
Abstract

It was shown in a previous paper1 that keratitis and cataract develop in albino rats restricted to a diet deficient in vitamin G, and it has also been shown2 that Norway rats respond in like manner. More recent experiments3 with modifications of the deficient diet yielded similar results. O'Brien3a has also reported cataract resulting from vitamin G deficiency. In order to demonstrate whether or not such deficiency lesions are common to mammals in general, other species have been subjected to a similar dietary regimen. The purpose of this paper is to report the production of cataract and other ocular changes in albino mice by the administration of a vitamin G-deficient diet. Bing and Mendel4 studied the effect of vitamin G deficiency on the albino mouse and reported that, in addition to dermatitis, the eyelids became inflamed and adherent in one animal.5

EXPERIMENTAL WORK

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