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October 1933


Author Affiliations


Arch Ophthalmol. 1933;10(4):520-534. doi:10.1001/archopht.1933.00830050096013

The observation which made Argyll Robertson's name famous was published in two articles. The first one, twelve pages long, appeared in 1869, in the Edinburgh Medical Journal and was entitled, "On an Interesting Series of Eye Symptoms in a Case of Spinal Disease, With Remarks of the Action of Belladonna on the Iris and So Forth." In this paper four points were emphasized : miosis, the effect of atropine and physostigmine (eserine) on the iris, color blindness and condition of the retinal vessels. The other paper, published in the same journal, was entitled, "Four Cases of Spinal Myosis, with Remarks on the Action of Light on the Pupil." Four cases were reported. Argyll Robertson stated that "these four cases serve well to illustrate the connection between certain eye symptoms and a diseased condition of the spinal cord." As regards the nature of the spinal lesion, in one case the characters of

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