It is apparent, from the reports in the ophthalmic literature, that the subject of angioid streaks has assumed, in the past few years, increasing interest. This is evident from the number of cases reported and the association of the streaks with a rather rare cutaneous disease known as pseudoxanthoma elasticum (elastorrhexis of the skin), in practically all the recent cases. Whether or not the occurrence of the two conditions is a coincidence, or whether, as some authors have concluded (Marchesani and Wirz, F. Poos, Gronblad), the two conditions are clinical manifestations of the same pathologic process, remains to be proved. The histopathology of angioid streaks is unknown, and virtually the same may be said for pseudoxanthoma elasticum. The purpose of this communication is to report two additional and typical cases of angioid streaks, both of which showed the definite cutaneous lesions of pseudoxanthoma elasticum.
Up to 1927,