In a series of experiments on animals, the primary purpose of which was to determine the effect of a rachitogenic diet on dental caries.1 ocular changes were noted in all the rachitic pups but in none of the normal controls. These findings suggested a relationship between rickets and the ocular lesions observed. To determine whether such a relationship did exist, and to study further the pathologic process in the eye in this dietary deficiency, we conducted a series of experiments, the results of which are described in this paper.
In the first experiment, five pups, 8 weeks old, were used. Two were fed a normal diet, and three received a rachitogenic diet for twenty-nine weeks. In the second experiment, four pups, three on a rachitogenic and one on a normal diet, were used. In the third experiment, five pups were fed a rachitogenic diet ; three died of