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To the Editor.—Relative to Dr. Joseph Levine's article on pellagra as a cause of optic neuritis, which appeared in the December issue of the Archives (12: 902, 1934), may I answer Dr. Levine's query concerning the changes in the fundi in cases of pellagra by stating that I do not know of any published work on the subject? It happens that in my work as consultant to the South Carolina State Hospital for the Insane I see a fair number of cases of pellagra. An examination of the eyegrounds is required for every patient admitted to the hospital. My impression is that there are no typical changes in the eyegrounds of pellagrins.
A great many pellagrins have other pathologic conditions along with pellagra. There have been several cases in which there were degenerative retinal and choroidal conditions which were thought to be due to a toxic focus
Bristow WJ. PELLAGRA AS A CAUSE OF OPTIC NEURITIS. Arch Ophthalmol. 1935;13(1):99. doi:10.1001/archopht.1935.00840010109012
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