The most frequent primary source of metastatic carcinoma of the choroid is the female breast. In the cases collected by Krukenberg1 and Behr2 about 70 per cent of the metastatic lesions originated from this organ. A later estimate by Usher3 indicated a similar incidence in a larger group of cases. The lung and the stomach are next in order of frequency as primary seats of the growths, while isolated instances have been reported of tumors metastatic from the liver, the mediastinum, the thyroid gland, the suprarenal glands and the prostate.4
The case to be described differs from those previously reported in that the primary malignant growth was an adenocarcinoma of the testis. This tumor belongs to the group of teratoid tumors of the testis. These embryonal tumors in which there is a sudden overgrowth of primary elements of the germ layer are highly malignant. While in
GOLDSTEIN I, WEXLER D. METASTASIS IN THE CHOROID FROM ADENOCARCINOMA OF THE TESTIS. Arch Ophthalmol. 1935;13(2):207–211. doi:10.1001/archopht.1935.00840020067007
Customize your JAMA Network experience by selecting one or more topics from the list below.