Orbital myositis in cases of exophthalmic goiter has been reported by Naffziger.1 In all his cases thyroidectomy was followed by subjective relief, but in the course of several months there was progressive increase of exophthalmos. The basal metabolic rate following the operation was minus in each case. The extra-ocular muscles were seen to be from three to eight times their normal size and showed microscopically varying degrees of muscular degeneration, edematous fibrosis and cellular infiltration. Friedenwald2 examined the extra-ocular muscles in six cases of hyperthyroidism in which the patient came to autopsy. In five of these cases the muscles were normal ; in one case, however, in which exophthalmos had preceded by several months all other manifestations of hyperthyroidism, the extra-ocular muscles showed changes similar to those described by Naffziger. This case differed from those reported by Naffziger in that there was no operation followed
REESE AB. DACRYADENITIS IN HYPERTHYROIDISM. Arch Ophthalmol. 1935;13(5):855–857. doi:10.1001/archopht.1935.00840050133013
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