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Article
May 1936

HISTOLOGY OF THE EXTRA-OCULAR MUSCLES

Author Affiliations

BOSTON
From the Howe Laboratory of Ophthalmology, Harvard University, and the Massachusetts Eye and Ear Infirmary.

Arch Ophthalmol. 1936;15(5):847-858. doi:10.1001/archopht.1936.00840170059007
Abstract

The purpose of this communication is to analyze the histology of the extra-ocular muscles with special reference to the possibility of ocular proprioceptive sense in man. Many isolated reports on the extraocular muscles have appeared in the literature, but they do not seem previously to have been brought together and correlated.

THE EMBRYOLOGY

First, the embryology of the extra-ocular muscles will be reviewed briefly.1 In the 7 mm. human embryo these muscles are seen as a single, undifferentiated, massed condensation of paraxial mesoderm surrounding the optic vesicle. At this stage the third nerve enters the anterior part of the muscle mass, dorsal to the optic stalk. At 9 mm., the mass is enlarged and begins to split into different muscles, with their respective nerves entering the dividing muscle mass. At 14 mm., all the muscles are formed and in about the same position with respect to the

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