Epithelioma of the conjunctiva may vary in malignancy, but in about 80 per cent of the cases it tends to recur, even when superficial. If the diagnosis is made early, it is proper to remove the tumor; but if the eyeball itself is involved, complete enucleation of the globe, together with exenteration of the remainder of the orbital contents, is indicated. Some form of radiation therapy should be employed after following surgical intervention.
Malignant growths in the bulbar conjunctiva are often the result of extension from a primary focus in the conjunctiva of the lid. This primary focus may be a nevus, which is a congenital growth usually considered benign. It is a smooth, flat tumor highly pigmented with melanin. The color may vary from light to dark red-brown. These nevi of the conjunctiva have much the same structure histologically as that of the ordinary pigmented nevi found on the
VANDEVERE WE, SPEARMAN MPS. MELANOCARCINOMA OF THE CONJUNCTIVA: REPORT OF A CASE. Arch Ophthalmol. 1936;16(1):46–50. doi:10.1001/archopht.1936.00840190056006
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