Neoplastic tumors that occur within the orbit can be classified on the basis of origin into three types as follows: (1) a primary tumor, one that originates within the orbit from tissue normal to that region or from bits of misplaced embryonic remnants; (2) a metastatic tumor, the original cells of which are brought to the orbit by the blood or lymph stream from a primary growth in a structure elsewhere in the body, and (3) a tumor resulting from invasion of the orbit by direct extension through the orbital walls or orifices by a neoplastic process in a contiguous region. This classification is only of clinical significance, for these tumors include tissue representative of a large proportion of the various neoplastic diseases of the body. Carcinoma and sarcoma representative of all types of this classification occur within the orbit with relative frequency, while highly differentiated malignant growths,
BENEDICT WL. ADENOCARCINOMA OF THE ORBIT. Arch Ophthalmol. 1936;16(4):663–671. doi:10.1001/archopht.1936.00840220121012
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