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February 1937


Arch Ophthalmol. 1937;17(2):347-350. doi:10.1001/archopht.1937.00850020153012

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Before the treatment of trachoma is reviewed a few general facts regarding the disease itself will be briefly stated.

Trachoma is contagious, and therefore its secretions can readily infect, either directly or indirectly, the conjunctivae of many persons. Its cause is still unknown ; therefore, the diagnosis rests on the clinical symptoms appearing at any stage of the disease. In its early stages it may be devoid of acute manifestations, but there may be superimposed or mixed infections, demonstrable by bacteriologic examination. The primary pathologic sign of trachoma is papillary hypertrophy of the tarsal conjunctiva, manifest mainly on the upper lid, although both lids are usually involved. According to most authorities, trachoma results in cicatrization of the conjunctiva and atrophy of the tarsus, producing deformities of the lid. In the hypertrophic or the cicatrizatial stage of the disease, there is frequently corneal vascularization or pannus, causing deterioration of vision or even

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