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Article
March 1937

CATARACT DUE TO DINITROPHENOL: REPORT OF CASES

Author Affiliations

SAN FRANCISCO

Arch Ophthalmol. 1937;17(3):513-515. doi:10.1001/archopht.1937.00850030127011
Abstract

It has been estimated that the total number of reported cases of cataract that developed after the use of dinitrophenol is between sixty and one hundred.1 I wish to present a report of cases and the result of the treatment secured at Greens' Eye Hospital.

Between Feb. 23, 1935, and Sept. 9, 1936, my associates and I saw nineteen patients with cataract in both eyes which had developed after the use of dinitrophenol. In these nineteen patients cataracts were removed from twenty-five eyes. All the patients were women, a fact which is in accord with the literature on this subject. Most of them belonged to the better situated classes.

Horner pointed out that susceptibility to dinitrophenol varies widely, because cataract develops in only a small percentage of those who have taken the drug.1 I have found also that there may be a familial susceptibility. My associates and

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