The recent report of Cox1 on congenital head nodding and nystagmus has led me to question more closely in cases of nystagmus the history of other members of the family in an attempt to trace a hereditary element, even though no head nodding was present. I was extremely fortunate in obtaining the genealogy of four generations through the efforts of the mother of one of my patients with nystagmus. The history may be relied on, as the mother is very intelligent and closely questioned other members of the family.
She volunteered the information that the women never had the trouble, but seemed to transmit it to the males. She also mentioned that by some coincidence the fourth born, if a male, had the trouble which the earlier members escaped.
Glover LP. CONGENITAL NYSTAGMUS. Arch Ophthalmol. 1937;17(4):705–706. doi:10.1001/archopht.1937.00850040141011
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