In 1920 Axenfeld1 described a white circular line that he observed on the posterior surface of each cornea, about 1 mm. from the margin, in an otherwise normal person. This he placed in the plane of Descemet's membrane and gave to his finding the name embryotoxon corneae posterius.
There are several earlier reports concerning a similar condition. In 1895 Mager2 described a ringlike, gray-white opacity 2 mm. in width in the deepest layers of each cornea of a 4½ year old girl.
In 1898 Gloor3 reported the case of a 6¼ year old girl with many congenital anomalies of the face and extremities. The left eye was normal, but the right cornea showed an opacity 1 mm. in width, near the limbus, extending over two thirds of the cornea. The author did not mention in which layer the opacity appeared, but the drawing showed that it was
BLOCH F. EMBRYOTOXON CORNEAE POSTERIUS AXENFELD: REVIEW OF THE LITERATURE AND REPORT OF A CASE. Arch Ophthalmol. 1937;18(1):68–72. doi:10.1001/archopht.1937.00850070080009
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