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Article
October 1937

PATHOGENESIS OF DISCIFORM DEGENERATION OF THE MACULA

Author Affiliations

BOSTON; PROVIDENCE, R. I.
From the Howe Laboratory of Ophthalmology, Harvard University, and the Massachusetts Eye and Ear Infirmary.

Arch Ophthalmol. 1937;18(4):561-585. doi:10.1001/archopht.1937.00850100073008
Abstract

In 1875 Pagenstecher gave a description of the macroscopic and microscopic appearance of a macular lesion observed in an eye after its removal for adherent leukoma and secondary glaucoma. His descriptions and illustrations of this lesion leave little doubt that the eye was affected with what is now known as disciform degeneration of the macula. His is the first case of this disease that we were able to find recorded in the literature. He designated the condition chorioidioretinitis in regione maculae luteae. The first employment of the term degeneratio maculae luteae disciformis was by Oeller in 1905. In 1926 Junius and Kuhnt adopted this term, substituting, however, Netzhautmitte for macula lutea, and definitely established the condition as a disease entity. Other terms to designate the disease, employed prior to the publication of their monograph, are indicated by the titles in the appended bibliography. The term favored by

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