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There is a group of cases of chorioretinitis in which the cause remains undetermined ; the condition has been regarded as either inflammatory or degenerative, on the one hand, or due to constitutional causes, on the other.
Formerly most conditions of the eye, including coloboma, microphthalmus and other developmental defects, were regarded as inflammatory. Recently interest in heredity and developmental disturbances has been aroused, and many conditions have been found to be inherited. These changes in the eye follow the same laws as changes elsewhere. Nevus and birthmarks are disseminated deformities of tissue, localized in the mucous membranes, meninges, central nervous system and eyes. Heijl discusses the relation of tuberous sclerosis and neurofibromatosis to the formation of nevus in a most interesting way. The principal topics of this book, however, are retinitis exudativa externa, or Coats' disease ; congenital retinal detachment ; pseudoglioma (the formation of connective tissue posterior
Knapp A. Ueber Retinitis unbekannten Ursprungs nebst einer histopathologischen Studie über Misbildungen des Sehorgans. Arch Ophthalmol. 1937;18(6):1051–1052. doi:10.1001/archopht.1937.00850120185023
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