In the first study of this series1 it was found that in rabbits systemically inoculated with human tubercle bacilli the eye participated in the general body sensitivity developing after inoculation. Ocular sensitivity developed synchronously with cutaneous sensitivity, and, with minor variations, ran a fairly parallel course, the cutaneous sensitivity affording a reasonably accurate index of the sensitivity of the undiseased eyes. In the second study it was pointed out that when the normal rabbit was inoculated with tubercle bacilli in the anterior chamber and the primary tuberculous focus lay in the eye, ocular sensitivity began to develop about the second week after inoculation and reached its height in about four weeks. The eyes showed a slowly progressive tuberculous inflammation during the first few weeks, which became acute, with caseation and necrosis, as the ocular sensitivity developed to maximum. Active tuberculous inflammation and ocular sensitivity persisted steadily up
WOODS AC, BURKY EL, FRIEDENWALD JS. EXPERIMENTAL STUDIES OF OCULAR TUBERCULOSIS: III. RELATION OF CUTANEOUS SENSITIVITY TO OCULAR SENSITIVITY IN THE NORMAL RABBIT INFECTED BY INJECTION OF TUBERCLE BACILLI INTO THE ANTERIOR CHAMBER. Arch Ophthalmol. 1938;19(2):245–250. doi:10.1001/archopht.1938.00850140087010
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