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After a brief description of the clinical picture known as embolism of the central retinal artery, it is stated that the cause is generally to be found in lesions or disorders (1) of the heart and vessels (2) of the endothelium and (3) of the blood. It has been found that the sinking reaction of the erythrocytes is increased. A prophylactic agent containing an injectable extract prepared from fresh liver (camponol) has been found of value in some cases. Intravenous injections of eupaverin have been used successfully to relieve the spasm ; the action of the drug was found to be of three hours' duration, and it must be given during the first ten hours. A good therapeutic agent consists of eupaverin 0.03 Gm., atropine methylbromate 0.0003 Gm. and aminopyrine 0.15 Gm., which is given in tablets and suppositories. Many forms of treatment are described, with references to the