The term superficial punctate keratitis may be considered a general morphologic designation for multiple, small, discrete lesions of the cornea which affect only the epithelial and the immediate subepithelial tissues. Excluding those cases in which the condition is obviously due to various chemical irritants, there remain two clinical variants generally seen in the United States. Graves1 has described these as the subepithelial and the epithelial type. In the former, exemplified by the classic superficial punctate keratitis of Fuchs, the lesions are relatively few in number and centrally located on the cornea, with perhaps some "metastatic" lesions toward the corneal margins. These lesions are usually circular and slightly raised, with crenated edges, and are visible macroscopically. They cause some disturbance of Bowman's membrane or of the underlying stroma. The epithelial type consists of multiple tiny erosions occurring all over the cornea, especially at the margins. Only the epithelium
COWAN A, COWAN TH. SUPERFICIAL PUNCTATE KERATITIS: ITS TREATMENT WITH IODINE SOLUTIONS. Arch Ophthalmol. 1938;19(5):709–713. doi:10.1001/archopht.1938.00850170059003
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