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Dear Dr. Lemoine:—I enjoyed reading your article on "Ocular Manifestations of Endocrine Disturbance" in the Archives of Ophthalmology (19:184 [Feb.] 1938).
I should appreciate an explanation of your statement (page 188) that calcium disturbance may produce cataract.
How does an increase or decrease of calcium in the blood affect the transparency of the lens? As a matter of fact, the chemistry of the lens remains the same at all ages until opacification sets in.
Your statement that there is a close association between cataract and parathyroid tetany, while true, requires a rational explanation. It is not the mystic hormonal activity of the parathyroid gland that causes cataract in some cases of parathyroid tetany but the direct injury to the lens due to a concussion of the lens during the convulsion. The same is true of epileptic and eclamptic convulsions, which are associated with a higher incidence of
Brav A. OCULAR MANIFESTATIONS OF ENDOCRINE DISTURBANCE. Arch Ophthalmol. 1938;19(5):797–798. doi:10.1001/archopht.1938.00850170147012
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