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Article
July 1938

INFLUENCE OF VITAMINS AND DINITROPHENOL ON THE PRODUCTION OF EXPERIMENTAL CATARACT

Author Affiliations

SAN FRANCISCO
From the Department of Pharmacology and the Division of Ophthalmology of the Department of Surgery, Stanford University School of Medicine.

Arch Ophthalmol. 1938;20(1):30-36. doi:10.1001/archopht.1938.00850190042004
Abstract

In recent years investigations of the causation of cataract have largely turned from the clinical and the anatomic to the experimental methods of physiologic and biochemical investigation as applied to the lens. With the invention of the slit lamp in 1911 by Gullstrand, the anatomic field for the exploration of cataract was opened, and the extensive and detailed reports which have followed in regard to opacities of the lens of all types form a fairly useful classification of cataract on a morphologic basis. The experimental approach to the study of cataract has been more or less hampered, however, by an inability to produce cataract in animals with any degree of constancy. Naphthalene has been used to produce cataract, but it is inconstant in its action on the lens, and it is well known that other ocular tissues show changes after the administration of this chemical compound. Fortunately, a more satis

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