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In this treatise, issued as a supplement to the current volume of the Zeitschrift für Augenheilkunde (Kuhnt and von Michel), an introductory chapter is devoted to a general consideration of the factors, offensive and defensive, which play a part in allergic reactions and to definition of the terms and concepts applied. The author then considers, in turn, ophthalmic allergic reactions due to the instillation into the conjunctival sac of such medicaments as atropine, scopolamine and physostigmine and certain excipient vehicles, such as petrolatum and sesame oil ; to matter unintentionally involving the skin of the lids or the conjunctiva such as toxic (sic) menstrual, fish or cat's blood, dust, dander, feathers and animal, plant and flower "hairs," and to substances which have a general injurious effect in addition to a local reaction, such as substances which give rise to industrial idiosyncrasies, cutaneous allergies and allied conditions. There is a chapter on