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February 1939


Author Affiliations

From the Department of Ophthalmology, the Oscar Johnson Institute of the Washington University Medical School.

Arch Ophthalmol. 1939;21(2):239-260. doi:10.1001/archopht.1939.00860020043004

Although a tumor of the lacrimal gland was first examined microscopically in 1867, the knowledge of the subject was chaotic until the report of Warthin1 in 1901. In reviewing the literature at that time he found 132 cases of tumor of the lacrimal gland which had been reported under 44 different diagnoses. After carefully considering these reports, he concluded that practically all of these tumors could be classified as mixed tumors of endothelial origin, the confusion being due to their complex histologic structure. He was the first to suggest that tumors of the lacrimal gland are essentially the same tumor as are found in the salivary glands. Since his report, mixed tumor of the lacrimal gland has been generally accepted to be a definite clinical entity, similar pathologically to mixed tumor of the salivary glands.

Diseases of the lacrimal gland are so rare as to be clinical curiosities. The