Although much of the ophthalmic literature deals with papilledema, its unilateral occurrence is mentioned only in widely scattered papers. Unilateral involvement is relatively rare but is nevertheless important and presents a difficult diagnostic problem. When the condition is bilateral certain causes are almost automatically excluded. Many additional factors which complicate the diagnosis must be taken into consideration when the condition is limited to one eye. The term choked disk is assiduously avoided in this paper, because it is often taken to include papillitis or optic neuritis, an entity having a different causation, different pathologic characteristics and symptoms and, to a lesser extent, a different appearance and different sequelae. In their early stages the differentiation of the two conditions may be difficult or impossible. Since a clear understanding of the two conditions is important, for reasons which will be given later, a brief summary of their chief characteristics will be presented
SMITH EG. UNILATERAL PAPILLEDEMA: ITS SIGNIFICANCE AND PATHOLOGIC PHYSIOLOGY. Arch Ophthalmol. 1939;21(5):856–873. doi:https://doi.org/10.1001/archopht.1939.00860050140014
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