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May 1939

Die erblichen Hornhautdystrophien. Dystrophiae corneae hereditariae.

Arch Ophthalmol. 1939;21(5):899-900. doi:10.1001/archopht.1939.00860050183018

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In this exhaustive publication Bücklers presents a study of 129 personal cases of hereditary corneal dystrophy, observed in and around Württemberg, a country in Southern Germany comparable in size and population with New Jersey. He has uncovered 12 family trees, some going back to the middle of the seventeenth century and comprising 300 persons. This rich material has been thoroughly sifted, and as a result of his painstaking studies the author was able to settle definitely some pertinent questions.

The conclusions arrived at by him are here presented.

All hereditary corneal dystrophies can be reduced to three independent pathologic conditions : (1) granular (nodular) corneal dystrophy (dystrophia corneae granularis [Groenouw I, Fleischer and others] ) ; (2) macular corneal dystrophy (dystrophia corneae macularis [Groenouw II, Fuchs, Fehr, Fleischer and others]), and (3) lattice-like corneal dystrophy (dystrophia corneae reticulata [Haab, Dimmer and others]).

  1. Granular corneal dystrophy is a dominant hereditary disease, beginning in

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