The term epithelial plaque was originated by Lister and Hancock1 in 1903 to denote local hyperplasia and cornification of the conjunctival and the corneal epithelium. It is a rare pathologic lesion when affecting the eye. Many other names have been used in the literature for these lesions, such as tyloma (Gallenga2), cornification of the conjunctiva (Best3), keratosis (Mohr and Schein4) and conjunctival callosities (Saemisch5). However, epithelial plaque would seem to be the most desirable term, as it is noncommital with regard to the type of hyperplasia and its etiology.
It is usual for authors (Parsons6 and Duke-Elder7) to include under this name hyperplasias of several types. They were first described as occurring on the cornea by Bowman8 in 1849. Similar cases were described by Warlomont9 in 1860 and by Hocquart10 in 1881. Gallenga,2 Best,3 Mohr and Schein4 and
NICHOLLS JVV. EPITHELIAL PLAQUES OF THE CONJUNCTIVA AND THE CORNEA. Arch Ophthalmol. 1939;22(3):370–376. doi:https://doi.org/10.1001/archopht.1939.00860090036003
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