Hyaline bodies on the lamina vitrea of the choroid, the Drusen of the Germans, are familiar to every one who uses the ophthalmoscope or has studied ocular histopathology.
Their histogenesis has been a matter of discussion, and the subject has recently been brought up to date by Rones.1 It seems not to be universally known, however, that closely packed aggregations of hyaline bodies in the macular region may in some middle-aged or elderly persons result in more or less serious disturbance of vision. It is to this distinct clinical picture that we wish to call attention. Some notes will be added on two other conditions in which degenerative changes of the lamina vitrea are presumably one or perhaps the only causative factor.
Hyaline bodies occur frequently in otherwise normal eyes, becoming larger and more numerous as age progresses but being found occasionally in young persons. They become larger and
GIFFORD SR, CUSHMAN B. CERTAIN RETINOPATHIES DUE TO CHANGES IN THE LAMINA VITREA. Arch Ophthalmol. 1940;23(1):60–75. doi:10.1001/archopht.1940.00860130072007
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