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Article
February 1940

EXPERIMENTAL STUDIES OF OCULAR TUBERCULOSIS: IV. THE RELATION OF OCULAR SENSITIVITY, CUTANEOUS SENSITIVITY AND OCULAR ACTIVITY IN THE IMMUNE-ALLERGIC RABBIT

Author Affiliations

BALTIMORE
From the Wilmer Ophthalmological Institute of the Johns Hopkins University and Hospital.

Arch Ophthalmol. 1940;23(2):351-362. doi:10.1001/archopht.1940.00860130389007
Abstract

In previous communications the general problem of ocular tuberculosis was discussed1 and experiments were reported2 on the interrelation of ocular sensitivity, ocular activity and cutaneous sensitivity in normal rabbits inoculated with tubercle bacilli either systemically or in the eye.

In the first paper2a on experimental work it was pointed out that the undiseased eyes of rabbits systemically infected with tubercle bacilli participated in the general sensitivity to tuberculoprotein, or tuberculin, manifested by the other tissues of the body and that, with minor fluctuations, the ocular and the cutaneous sensitivity were fairly parallel.

In the second report2b it was noted that when the eyes of normal rabbits were infected by the injection of tubercle bacilli, ocular sensitivity to tuberculoprotein became apparent at the end of the second week and was maximal by the third week. The first reaction of the eyes was a slowly progressive tuberculosis with

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