In 1934 van der Hoeve1 reported 4 cases of a new disease which he had named scleromalacia perforans. Two of the cases were his own and the other 2 belonged to Rochat, who had independently named the condition scleritis necroticans.
Scleromalacia perforans was described as a degenerative disease, accompanied by little or no inflammation and characterized by the appearance of multiple holes in the sclera. Some of the holes were covered by conjunctiva. Others exposed bare uvea to the outside. Adjacent holes often coalesced. The patients in all 4 cases were elderly. Three had advanced chronic rheumatic polyarthritis. One never had had any symptoms of arthritis. Van der Hoeve also mentioned that he had heard of the existence of 2 more cases of this disease, although he had not seen either of the patients. Both were reported as being elderly, and 1 suffered from chronic arthritis.
Apparently all 4
EGGERS H. NECROSCLERITIS NODOSA ASSOCIATED WITH CHRONIC RHEUMATOID POLYARTHRITIS: REPORT OF CASE. Arch Ophthalmol. 1940;23(3):501–506. doi:10.1001/archopht.1940.00860130565004
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