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Article
March 1940

VACCINIA WITH OCULAR INVOLVEMENT

Arch Ophthalmol. 1940;23(3):584-590. doi:10.1001/archopht.1940.00860130650014
Abstract

Many cases of vaccinia involving the lids and cornea have been reported, so that the reports of 2 additional cases of vaccinia of the lids, which are included in this article, are of comparatively little interest.

The purpose of this paper is to discuss measures that offer some promise of inhibiting the action of the vaccinia virus or that will protect the cornea against becoming involved.

The incidence of inoculation of the lids or cornea is apparently small when one considers the large number of vaccinations that are done each year. However, many cases are probably not reported, and possibly some may not be recognized.

When ocular involvement does occur, the lids are usually the first to become affected, and the cornea is probably inoculated later by the virus from the lesions on the lids or the conjunctiva. However, a number of cases have been reported in which there has

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