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Article
April 1940

PRIMARY TUMORS OF THE OPTIC NERVE (A PHENOMENON OF RECKLINGHAUSEN'S DISEASE)A CLINICAL AND PATHOLOGIC STUDY WITH A REPORT OF FIVE CASES AND A REVIEW OF THE LITERATURE

Arch Ophthalmol. 1940;23(4):735-821. doi:10.1001/archopht.1940.00860130827006
Abstract

SECOND INSTALLMENT (MAY ISSUE)  General CommentNature of Gliomas as Revealed by This Study.Clinical FeaturesGlial Cells of the Normal Optic NerveClassification of Types of Gliomas Found Among Tumors of the Optic NerveRecklinghausen's DiseaseRelation of Tumors of the Optic Nerve to Recklinghausen's DiseaseA Review of the LiteratureCommentTable Summarizing the Review of the Literature on Recklinghausen's Disease and Tumors of the Optic NerveSummaryAcknowledgmentsBibliographyAbstract of Discussion

INTRODUCTION AND CLASSIFICATION  Primary tumors of the optic nerve are rare. Collins and Marshall reported only 2 over a period of fifteen years among 388,000 patients treated at the Royal Ophthalmic Hospital (Moorfields) in London. Verhoeff reported that 4 primary tumors of the optic nerve were removed at the Massachusetts Charitable Eye and Ear Infirmary over a period of thirty-six years, during which time 669,557 new patients were examined. In these two large series of

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