In 1910 Fleischer1 described the eyes of a 37 year old woman suffering from multiple sclerosis in an article entitled "A Peculiar Previously Unknown Opacity of the Cornea." The left amblyopic eye of this patient showed convergent strabismus. Refraction of both eyes revealed high hyperopia with considerable astigmatism at an oblique axis. The corneas showed identical changes. In the superficial layers there was a fine opacity covering the whole cornea. It consisted of rays or bundles converging toward a point slightly below the center of the cornea or radiating from that point toward the periphery, like a crown of human hair. The lower and upper halves of the cornea were separated by a narrow horizontal stripe of clear corneal tissue. Higher magnification showed that the opacity consisted of small yellowish brown points and spots and that the picture of the vortex figures was caused by clear spaces between these
BLOCH FJ. VORTEX-SHAPED DYSTROPHY OF THE CORNEA. Arch Ophthalmol. 1940;23(4):825–830. doi:10.1001/archopht.1940.00860130919008
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.