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Article
June 1940

RETINITIS PIGMENTOSA: ETIOLOGIC AND CLINICAL IMPLICATIONS BASED ON TWENTY-ONE CASES

Author Affiliations

DETROIT
From the Department of Medicine and the Department of Ophthalmology, Harper Hospital and Wayne University.

Arch Ophthalmol. 1940;23(6):1257-1273. doi:10.1001/archopht.1940.00860131417015
Abstract

Twenty-one cases of retinitis pigmentosa in which the familial history and certain physical characteristics were studied form the basis of this report. Because of the well known effect of the pituitary gland (pars intermedia) on the pigmentary system, it was felt that some clinical characteristics might be present which would link this gland with retinitis pigmentosa. Furthermore, owing to certain clinical findings, the embryologic development of the hypothalamic-pituitary and optic systems was thought to be of importance as giving a clue to the causation of this disease.

Involvement of the pituitary gland and the diencephalon in an etiologic role has been thought of by several investigators (Mamola and Bellina,1 Schupfer,2 Viallefont3 and others).

The essential features pertinent to the discussion are given in the accompanying table.

The ages of the patients ranged from 8 to 51 years, the average age being 32.2 years.

There were 11 males

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