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Article
July 1940

CORNEAL INVOLVEMENT IN CONGENITAL ICHTHYOSIS (KERATODERMA)

Author Affiliations

CINCINNATI
From the Department of Ophthalmology, College of Medicine, University of Cincinnati, and the Children's Hospital.

Arch Ophthalmol. 1940;24(1):215-220. doi:10.1001/archopht.1940.00870010237020
Abstract

A recent article by Cordes and Hogan1 dealt with ichthyosis of the skin and described a case in which corneal involvement of pannus-like nature was associated. The lesion covered the lower three fifths of the cornea, was sharply demarcated from the normal cornea above by a slightly raised, irregular border and passed interruptedly into the conjunctiva and sclera below. Vascular loops arising from the anterior ciliary and conjunctival vessels were a prominent feature. Severe and persistent photophobia and lacrimation were distressing symptoms.

From a study of this case and a brief analysis of the literature they concluded :

Involvement of the ocular tissues in cases of ichthyosis of the skin is rare and may occur in several forms :

  • There may be asymptomatic involvement of the cornea in the nature of dystrophy of the corneal cells and nerves. This form is seen only with the slit lamp or other means of

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