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Article
August 1940

STUDIES OF THE VISUAL FIELDS IN CONNECTION WITH TRYPARSAMIDE THERAPY

Arch Ophthalmol. 1940;24(2):276-280. doi:10.1001/archopht.1940.00870020068007
Abstract

In most institutions where syphilitic patients are treated with tryparsamide, the value of periodic ocular examinations is recognized. Many workers in this field control medication with tryparsamide largely by periodic examinations of the visual fields. The following study is intended to show the state of the visual fields before, during and after tryparsamide therapy in both syphilitic and nonsyphilitic patients.

Since Lorenz and his co-workers1 introduced tryparsamide in the treatment of neurosyphilis, the medical literature has contained a large number of reports concerning the effect of the drug on the visual mechanism. So contradictory have been these reports that one is at a loss to arrive at any definite conclusion as to the action of the drug on the eye. Woods and Moore,2 in their complete report of the visual disturbances produced by tryparsamide, recognized the toxic nature of the drug. Lillie,3 however, stressed the importance of

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