Since the discovery of the inclusion bodies of trachoma by Halberstaedter and Prowazek1 in 1907, the nature and the significance of intracellular bodies found in conjunctival epithelium have been the subjects of extensive investigation. In 1909 Stargardt2 reported finding bodies similar to those described by Halberstaedter and Prowazek in an infant with gonococci-free blennorrhea, and later, in cases of gonorrheal blennorrhea, Heymann3 found large numbers of the same bodies and considered them to be products of the gonococci. Wolbach and McKee,4 McKee,5 Isabolinsky and Spassky,6 Lumbroso,7 W. S. and P. M. Duke-Elder8 and others described so-called inclusion bodies in normal or slightly damaged conjunctival cells, and later Gifford and Lazar9 reported chemically induced inclusion bodies in the conjunctival epithelial cells of guinea pigs. From time to time many of these capable workers have retracted or amended their reports, however, and there
BRALEY A. INTRACELLULAR BODIES OF THE CONJUNCTIVAL EPITHELIAL CELLS. Arch Ophthalmol. 1940;24(4):681–690. doi:10.1001/archopht.1940.00870040067005
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.