In 1907 Halberstädter and von Prowazek first described the cellular inclusions associated with trachoma. In 1909 Stargardt1 found similar inclusions in cases of blenorrhoea neonatorum ; indeed, the bodies of inclusion blenorrhea cannot be distinguished from those of trachoma on morphologic grounds. Leber and von Prowazek2 in 1912 published a report on a disease of man, probably trachoma, in the South Sea islands and called the inclusions Lyozoon atrophicans, a species of Chlamydozoa.
Shortly after these discoveries were made Uhlenhuth and Böing,3 in 1910, stated that they had found bodies in the conjunctival epithelium of pigs and that these bodies closely resembled the inclusions of trachoma and blenorrhoea neonatorum. From this time onward various German workers4 linked these structures, closely or loosely, with the virus of swine fever or hog cholera. These hazy perceptions still persist in many quarters. Von Buzna,5 however, failed to detect the
COLES JDWA. A RICKETTSIA-LIKE ORGANISM OF THE CONJUNCTIVAL EPITHELIUM OF PIGS. Arch Ophthalmol. 1941;25(1):101–112. doi:10.1001/archopht.1941.00870070115012
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.