Many different treatments have been used in an attempt to improve the loss of vision due to atrophy of the optic nerve. Up to the present time little hope for improvement has been given. After a review of the literature two years ago, it was decided to try at the University of Arkansas School of Medicine the treatment described by Fejér,1 Kosmin,2 Lauber3 and Cordes.4 This treatment consists of retrobulbar injections of a solution of atropine. The only rational reason that improvement could be expected from this treatment in cases of atrophy of the optic nerve would seem to be that it increases the arterial circulation to this nerve. Several different types of atrophy were treated by this method. The outline of treatment given by Kosmin2 was used. This consisted of the injection of a 0.1 per cent aqueous solution of atropine sulfate into the
COSGROVE KW, McCALL EF. RETROBULBAR INJECTIONS OF ATROPINE SULFATE FOR ATROPHY OF THE OPTIC NERVE. Arch Ophthalmol. 1941;25(5):814–818. doi:10.1001/archopht.1941.00870110066006
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