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Article
September 1941

TREATMENT OF STAPHYLOCOCCIC BLEPHAROCONJUNCTIVITIS WITH STAPHYLOCOCCUS TOXOID

Arch Ophthalmol. 1941;26(3):430-434. doi:10.1001/archopht.1941.00870150104006
Abstract

A previous report1 summarized the results of treatment with staphylococcus toxoid in 57 cases of conjunctivitis in which toxinproducing staphylococci had been isolated. In 46 of these cases no other etiologic factors were found, but in the remaining 11 there were such associated factors as acne rosacea, cicatricial trachoma and allergy. In each case the conjunctivitis was long standing and had resisted local treatment for not less than two months. During the course of treatment with toxoid the local treatment which had previously failed was continued. Twenty-one of the 57 patients showed healing; 19 showed clinical improvement, and 17 showed no improvement. In only 24 of the 57 cases did the cultures become negative for toxin-producing staphylococci. Eight of the 21 patients in whom healing had occurred suffered a recurrence of symptoms; these symptoms disappeared after a second course of toxoid therapy. Recurrence appeared to be related to persistence

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