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Article
August 1942

SEASONAL VARIATIONS IN PHOSPHOLIPID CONTENT OF CRYSTALLINE LENSESWITH SPECIAL REFERENCE TO CLIMATOLOGIC INFLUENCES

Arch Ophthalmol. 1942;28(2):254-257. doi:10.1001/archopht.1942.00880080072008
Abstract

In two previous publications1 experiments were described showing that the cholesterol and the phospholipid content of crystalline lenses varied more or less inversely to each other and that the cholesterol content varied also inversely to the humidity of the atmosphere. Opinion was then expressed that consequently the phospholipids should vary directly with humidity. Analyses for phospholipids of cataractous lenses from patients all of whom resided in the state of Iowa were made for twenty-five consecutive months beginning with November 1933 and ending with November 1935. The ages of the subjects from whom the lenses were obtained varied from 31 to 87 years, with an average of 68 years. In all, 240 lenses, extracted by the intracapsular method, were analyzed. The analyses were carried out by a modification of Whitehorn's colorimetric method,2 and the phospholipids were calculated as lecithin. The number of lenses collected each month varied from 2

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