In 1932 Adie1 described a syndrome consisting of tonicity of the pupils and absence of tendon reflexes. This syndrome manifests itself in several clinical forms, which are referred to as complete and incomplete. The complete form is characterized by the presence of the tonic convergence reaction in a pupil apparently inactive to light and by absence or diminution of one or more of the tendon reflexes of the lower limbs. The incomplete forms exhibit (1) the tonic pupil alone, (2) atypical phases of the tonic pupil alone, (3) atypical phases of the tonic pupil with absence of tendon reflexes and (4) absence of tendon reflexes alone.
No hereditary or acquired morbid factor is known to play any part in production of the syndrome. In particular there is said to be no relation to syphilis. The syndrome runs a benign course without the addition of further symptoms and is compatible