The term rosacea keratitis was long ago applied to a condition frequently observed in patients having acne rosacea. This condition is characterized by the presence of one or more small peripheral infiltrates, between which and the limbus a number of small capillaries appear, progressing almost to, but not quite touching, the infiltrates. It was popularized by Doggart,1 and his descriptions and illustrations of the advanced pathologic changes have caused many ophthalmologists to consider only the advanced stage as "rosacea keratitis." It has long been observed that Negroes and other patients without dermatologic acne rosacea may have severe lesions. In fact, the incidence without acne rosacea is so much greater that the occurrence with it is now considered almost a coincidence, although in general the lesions accompanying acne rosacea are of greater severity and without the aid of riboflavin are much more destructive of the visual function.
Much smaller infiltrates,
CONNERS CA, ECKARDT RE, JOHNSON LV. RIBOFLAVIN FOR ROSACEA KERATITIS, MARGINAL CORNEAL ULCERS AND CATARRHAL CORNEAL INFILTRATES: LABORATORY AND CLINICAL STUDIES. Arch Ophthalmol. 1943;29(6):956–967. doi:10.1001/archopht.1943.00880180106009
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