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Article
June 1943

SULFONAMIDE COMPOUNDS IN OPHTHALMOLOGY

Arch Ophthalmol. 1943;29(6):1023-1025. doi:10.1001/archopht.1943.00880180173016

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Abstract

To the Editor:  —In the Sept. 12, 1942 issue of the British Medical Journal (page 314) an editorial entitled "The Sulphonamides in Ophthalmology" summarized some of the recent publications on the value of the sulfonamide compounds in the treatment of ocular infections. May I point out some of the opinions which do not correspond with the ones I have found to exist?The editorial stated :The sulphonamides, with their largely selective actions on the streptococcus, pneumococcus, meningococcus, and gonococcus, would not, therefore, appear to be promising in combating anything beyond the microbial infections of this type seen in the conjunctiva. . . . The most striking results are seen in ophthalmia neonatorum. . . . In practice sulphapyridine [2-(paraaminobenzenesulfonamido)-pyridine] proved remarkably effective in all types of ophthalmia neonatorum. . . . The results in ophthalmia neonatorum are so uniformly good that bacteriological examination to establish the identity of the causal organism is almost superfluous. . . .The sulfonamide compounds are effective

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