Although ocular complications following vaccination are not rare, they are uncommon, and it is thought timely to call attention to the omnipresent possibility of their occurrence.
Their mode of occurrence may be of two types : autoinoculation, in which there is direct transfer of the virus from the site of vaccination to the eyes ; and heteroinoculation, in which the virus is transferred from one person to another.
The lids, conjunctiva or cornea may be involved; of these, involvement of the cornea is most serious, since in this type impairment of vision may result. In approximately one third of the reported cases of vaccinia with ocular complications the cornea has been involved.1
REPORT OF A CASE
G. B., an 8 year old white boy, was first seen on May 5, 1943. One week before he had been vaccinated on the right arm. Three days after the vaccination the patient noted redness
Klunzinger WR. AUTOINOCULATION OF THE EYELIDS WITH VACCINIA. Arch Ophthalmol. 1944;31(6):539–540. doi:10.1001/archopht.1944.00890060111009
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.