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Article
May 1945

INHERITED CATARACT IN THE B. GENEALOGY: OCCURRENCE OF DIVERSE TYPES OF CATARACT IN THE DESCENDANTS OF ONE PERSON

Author Affiliations

ROCHESTER, N.Y.
From the Departments of Surgery and Medicine, the University of Rochester School of Medicine and Dentistry, and the Strong Memorial and Rochester Municipal Hospitals.

Arch Ophthalmol. 1945;33(5):341-357. doi:10.1001/archopht.1945.00890170017001
Abstract

The numerous publications on developmental cataract, as summarized by Nettleship,1 Harman,2 Groenouw,3 Clausen,4 and Waardenburg,5 have tended to show a uniformity in the type of cataract observed within any family line. Nevertheless, it is sometimes found that certain of the cataractous persons in a given pedigree have a type of opacity of the lens significantly different from that presented by the remaining affected members of the family (Knies,6 Gjersing, 1878, quoted from Harman,2 Nettleship, Harman,8 Groenouw,3 Halbertsma,9 Walsh and Wegman10). This fact has been commented on by various observers, and a question raised from time to time as to the etiologic relationships of the various types. The present paper will de- scribe a genealogy of 123 people, 44 with cataract, which is remarkable for the variety of forms the cataract assumes, and will discuss the question of the genetic

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