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September 1945


Arch Ophthalmol. 1945;34(3):248. doi:10.1001/archopht.1945.00890190248012

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To the Editor:  —In a recent report (An Unusual Type of Keratitis Associated with the Exposure to N-Butyl Alcohol [Butanol], Arch. Ophth.33: 106 [Feb.] 1945) describing keratitis in 28 workers exposed to n-butyl alcohol (butanol), we overlooked an article by M. Bücklers (Tröpfchenförmige Niederschläge auf der Hornhautoberfläche bei Möbelarbeitern, Klin. Monatsbl. f. Augenh.99: 676, 1937) describing what appears to have been the same condition in 7 furniture lacquerers. The causative agent was unknown to Bücklers, since the composition of the lacquer was an industrial secret ; but the author's description of vacuoles ("not larger than 40 microns") situated symmetrically in the epithelium of otherwise clear corneas, the occurrence of severe epiphora, burning and watering of the eyes, and the complete reversibility of the process when the patients stayed away from their work leave little doubt that the keratitis which we described in connection with the use of n-butyl alcohol

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