It has been stated by Virchow that organs which are a frequent site of origin of primary cancer are prone not to have metastatic growths. Although it is now recognized that there are many exceptions to this statement, the rule seems to apply with peculiar force to the melanotic malignant growths of the eye. Most of the melanomas of this organ are known to be primary in the choroid. Only a few have been reported as metastasizing to the eye from other sites of origin. Recently there came under observation at City Hospital a patient with the unusual occurrence of a melanotic tumor arising in the skin and producing intraocular metastases. In addition, his case presented the unique feature of metastasis to the orbital tissue. This case forms the basis of the present report.
REPORT OF CASE
—A white man aged 68 was admitted to the first medical division,
LISA JR, GIVNER I. MELANOMA OF THE SKIN WITH INTRAOCULAR AND ORBITAL METASTASES: REPORT OF A CASE. Arch Ophthalmol. 1945;34(5):422–424. doi:10.1001/archopht.1945.00890190426015
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