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January 1946

Le penicilina y sus aplicaciones en oftalmologia.

Arch Ophthalmol. 1946;35(1):62. doi:10.1001/archopht.1946.00890200066017

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This small book cites the importance of this new drug in clinical work and then gives a short and rather fanciful sketch of Alexander Fleming's early life.

There follows an account of his discovery and the application of the drug, its effects, toxicity and dosage. Its applications in ophthalmology are reported, and the author's method, preferably by intramuscular injection, is submitted, he preferring that means to use of collyriums or ointments and reporting cases thus cured. He concludes that the drug is a prophylactic against ocular infection before operations.

The author recommends in 2 cc. the intramuscular injection of 20,000 units every three hours. The remedy has been tried by the author in treatment of various infections and of conditions in which the cause was obscure. He thinks that the treatment is particularly of value before operations, when he recommends that five injections be given, one at the time of

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