THE value of local applications of solutions of penicillin in the treatment of certain inflammatory diseases of the eye is now generally recognized. Experimental and clinical evidence has shown this to be particularly true in cases of diseases of the anterior segment of the globe.1 Experimentally, in cases of this type relatively high concentrations of penicillin in the cornea, conjunctiva, sclera, aqueous, iris and ciliary body and small amounts in the vitreous can be built up by use of the corneal bath and by subconjunctival injection.2 High degrees of penetration of penicillin have also been attained with iontophoresis.3
It has been our experience that administration of penicillin as eye drops by simple instillation will effect the prompt cure of the acute inflammatory diseases of the conjunctiva caused by penicillin-sensitive organisms.2 In the treatment of corneal ulcers, however, particularly in cases in which the deeper layers
STRUBLE GC, BELLOWS JG. CONTACT EYE CUP FOR CORNEAL BATHS WITH SOLUTIONS OF PENICILLIN. Arch Ophthalmol. 1946;35(2):173–175. doi:10.1001/archopht.1946.00890200178010
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